Caseous lymphadenitis is a chronic, recurring disease in goats. A slowly enlarging, localized, and nonpainful abscess may develop either at the point of entry into the skin or in the regional lymph node (superficial or external form), from which it may spread via the blood or lymphatic system and cause abscessation of internal lymph nodes or organs. Economic losses result from reduced weight gain, reproductive efficiency, and wool and milk production, as well as from condemnation of carcasses and devaluation of hides.

Infection may occur after C pseudotuberculosis penetrates through unbroken skin or mucous membranes; however, in most cases it probably begins when superficial skin wounds are contaminated with purulent material from ruptured abscesses from other sheep and goats. Ruptured superficial and lung abscesses are the primary sources of environmental contamination. Contaminated dipping vats and shearing, handling, and feeding equipment are responsible for spread of the organism. The pus contains large numbers of bacteria that can survive for months in hay, shavings, and soil.

Autogenous CL works by boosting immunity to the specific organism you have on your ranch. A sample of the exudate (pus) from an abscess is collected, then isolated. From this sample, PHL will produce a vaccine that is tailor-made to combat the specific strain(s) which have infected your animals. Autogenous CL Vaccine is a killed bacterin toxoid which is administered subcutaneously. It is initially administered in 2 doses, followed by annual (single dose) boosters. The adult dose is 2cc’s and a kid’s dose is 0.5 to 1 cc. Autogenous Goat CL Vaccine is available in two sizes. The 250 mL bottle contains about 125 doses, and the 100 mL bottle contains about 50 doses. Since CL is a "killed" vaccine, an annual booster (single dose) vaccination is required.

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